15 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... #Peripheral #Blood ... #Smear #Analysis ... #hematology #microscopy
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... polychromatophilic cells ... arrow) Peripheral smear ... Hematology #Pathology #Smear ... #Microscopy
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
- Differential ... • Peripheral blood ... smear + DAT + further ... History • Bite cells ... #Differential #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Peripheral Smear ... Workup: • Complete ... differential • ... smear • Bone marrow
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
• stored red blood ... cells - Hb variant ... - Sickle cell anemia ... Dissociation #Curve #Pathophysiology ... #Right #Shift #Differential
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Algorithm Normal Blood ... Smear • Drugs ... Macrocytosis, Target Cells ... #elevatedMCV #Differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... plateletcount), peripheral blood ... smear, HIV/HCV ... changes), high MCV anemia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Peripheral Smear ... hematology for workup ... hematologic: Acute blood ... hemolysis, deficiency anemia
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
oxygen in the blood ... SvO2 → Low PaO2 ANEMIC ... CYTOPATHIC HYPOXIA - Cells ... summary #pulmonary #differential ... diagnosis #causes #pathophysiology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... of Peripheral blood ... smear - Shows schistocytes ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup