49 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... : Acute blood loss ... Rebound effect from treatment ... #Differential #Diagnosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... drug reaction, infection ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... cells + production ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Some of the techniques used for Antenatal Diagnosis

Amniocentesis 
 - Chromosome/micro-array and DNA analysis 
 -
— PCR Fetal blood ... serology - Fetal blood ... genetic analysis of cells ... surgery, e.g. laser photo-coagulation ... from maternal blood
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... • Parvovirus infection ... factor (GCSF) treatments ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... risk-stratification • Risks: infection ... only curative treatment ... #Management #treatment ... #hematology #oncology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... and laboratory diagnosis ... polychromatophilic cells ... hemolytic #anemia #Hematology ... Pathology #Smear #Microscopy
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
- Differential Diagnosis ... Algorithm Red blood ... cells on urine ... microscopy. ... glomerulonephritis • Post-Infectious
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... the total white blood ... similarly to mast cells ... #Differential #Diagnosis ... #causes #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Immunoglobulin M (IgM) • Blood ... sensitize red blood ... cells (RBCs) at ... hemolytic #anemia #hematology ... #diagnosis