32 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Cytokines, Mast Cells ... perivascular inflammatory cells ... Vasculitis #HUV #Pathophysiology ... #Rheumatology
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
convoluted tubule cells ... , principal cells ... and intercalated cells ... #Pathophysiology ... NephronRemodeling #NEJM
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... criteria for 1) hematologic ... hematopoietic stem cells ... blood myeloid cells ... NEJM Review: https
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... germinative skin cells ... Skin-homing T-cells ... #Diagnosis #Dermatology
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... the sickle red cells ... SickleCell #Disease #Pathophysiology ... Complications #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... Lymphocyte - 5% RS cells ... (LP) tumour B cells ... Classification #pathophysiology ... #Hematology #Diagnosis
Urinary Tract Tuberculosis - Contrast-enhanced computed tomography (CT) of the abdomen showed mild dilatation of the
the left renal pelvis ... D) #Clinical #Radiology ... AcidFastBacilli #Microscopy #NEJM
Non-cirrhotic Hyperammonemia - Differential Diagnosis Framework

Hematologic & Vascular:
 • Multiple myeloma & Acute leukemia (plasma cells
Diagnosis Framework Hematologic ... leukemia (plasma cells ... Differential #Diagnosis #Pathophysiology
Hemolysis in Hereditary Spherocytosis. Panel A shows the structure of a normal red cell and a
spleen in which red cells ... between endothelial cells ... #Pathophysiology ... HereditarySpherocytosis #NEJM
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
and endothelial cells ... diagnosis #models #hematology ... #pathophysiology