19 results
diagnosis oncology differential management algorithm leukemia causes chronic clinical cll hemolytic lymphocytic mds myelodysplastic pancytopenia pathology acquired agglutinin analysis autoinflammatory
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood Smear ... Sickled red cells ... Peripheral #Blood #Smear ... #Analysis #hematology ... #microscopy #interpretation
A non-subtle example of true Sezary syndrome. Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Constitutional Syndromes ... anemia Treatment ... #hematology #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Peripheral Smear ... → Refer to hematology ... for workup, including ... hemolysis, deficiency anemia ... Diagnosis #Algorithm #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... polychromatophilic cells ... arrow) Peripheral smear ... #Hematology #Pathology ... #Smear #Microscopy
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... HLH syndrome 5. ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... Diagnosis #Algorithm #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... = funny-shaped cells ... cytopenias (usually anemia ... #hematology #oncology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... HLH syndrome 5 ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... Diagnosis #Algorithm #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Peripheral Smear ... • Aplastic Anemia ... Workup: • Complete ... #diagnosis #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... Abnormalities: macrocytic anemia ... criteria for 1) hematologic ... NEJM Review: https ... Autoinflammatory #Somatic #rheumatology
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