12 results
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
Large Granular Lymphocytic ... are NK cells (sCD3 ... LargeGranular #Lymphocytic ... #Leukemia #hemepath ... #pathology #diagnosis
IgG4-associated conditions

Diagnosis of IgG4 disease is depending on BIOPSY. While IgG4 levels can be informative (and
conditions Diagnosis ... really need to see pathology ... positive plasma cells ... and lymphocytes ... Even the pathology
Cryptococcus neoformans Meningoencephalitis- The opening pressure on lumbar puncture was 29 cm of water (reference range,
count was 340 cells ... 90% mononuclear cells ... predominantly lymphocytes ... #clinical #NEJM ... stain #indiaInk #pathology
Acute Rheumatic Fever with Erythema Marginatum - Painless, nonpruritic, red annular macules appeared on the upper
infiltration of lymphocytes ... #Clinical #Derm ... #Pathology #Erythema ... ErythemaMarginatum #Microscopy #NEJM
Tinea Capitis in a Newborn- A 3-week-old male newborn was brought to the pediatrician with three
ringworm, was diagnosed ... #clinical #photo ... #NEJM #tinea #capitis ... #ringworm #derm
Indolent T-Lymphoblastic Proliferation (iT-LBP)
Features of iT-LBP:
 - May be seen in association with other malignancies (e.g.
Groups of TdT+ T-cells ... Proliferation #Hemepath ... #pathology #Clinical ... #diagnosis
Adult T-cell Leukemia / Lymphoma (ATLL) - Mimicking Angioimmunoblastic T-cell lymphoma with Hodgkin like cells

Features ATLL:
with Hodgkin like cells ... Leukemia #Lymphoma #Hemepath ... #pathology #Clinical ... #diagnosis
Disseminated Cutaneous Blastomycosis- A fungal culture of skin tissue was negative; however, a skin biopsy showed
staining confirmed a diagnosis ... #clinical #photo ... #derm #NEJM #cutaneous
Brittle nails and hair loss in hypothyroidism- ...Physical examination revealed dry skin, thickened and brittle nails
Hashimoto’s (chronic lymphocytic ... thyroiditis was diagnosed ... the differential diagnosis ... #clinical #photo ... #NEJM #hypothyroidism
Grouped Pustules on an Erythematous Base - On physical examination, grouped, coalescing pustules that had scalloped
multinucleated giant cells ... #Clinical #Derm ... #Pathology #Herpes ... Smear #Microscopy #NEJM