64 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
thrombocytopenia, multiple myeloma ... conditions - multiple myeloma ... hematopoietic stem cells ... peripheral blood myeloid ... cells NEJM Review
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma ... Diagnosis and Management ... osteolytic lesions and pathologic ... marrow plasma cells ... #Multiple #Myeloma
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
T-PLL) not Acute Myeloid ... 🔬Tumor cells are ... size lymphoid cells ... Smear #Peripheral #Pathology
Comparison of basophils and mast cells (in bone marrow).

#Basophils #MastCells #Pathology #Marrow #Smear #Microscopy #Comparison #Table
basophils and mast cells ... Basophils #MastCells #Pathology ... Table #Clinical #Diagnosis
Back Pain - Differential Diagnosis
Primary Back Pathology:
 • Musculoligamentous injury (a.k.a. lumbosacral strain)
 • Spondylosis (i.e.
- Differential Diagnosis ... Primary Back Pathology ... compression fracture, Pathologic ... , thyroid, and myeloma ... #Differential #Diagnosis
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
Dacrocytes (tear drop cells ... each of the above photos ... myelofibrosis, myeloid
Urinary Tract Tuberculosis - Contrast-enhanced computed tomography (CT) of the abdomen showed mild dilatation of the
the left renal pelvis ... Clinical #Radiology #Pathology ... AcidFastBacilli #Microscopy #NEJM
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
Diffuse plasma cells ... cell disorders (myeloma ... Disease #Variants #Diagnosis ... #Pathology
Herpes Zoster Mandibularis - The lesions were scattered along the area that is innervated by the
A presumptive diagnosis ... #Clinical #Photo ... Mandibularis #Rash #NEJM
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
POEMS syndrome, myeloma ... Leah Willis via ... #differential #diagnosis