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differential clinical management dermatology algorithm oncology rheumatology syndrome treatment anemia hepatology rash signs blood microscopy neurology pathophysiology skin skinrash smear
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... criteria for 1) hematologic ... conditions - multiple myeloma ... peripheral blood myeloid ... cells NEJM Review
Hypersegmented neutrophil in a case of acute myeloid leukemia. Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case ... of acute myeloid ... AML #Clinical #Hematology ... #Pathology #Smear
Prolymphocytes In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML). 🔬Tumor
Prolymphocytes In our case ... T-PLL) not Acute Myeloid ... 🔬Tumor cells are ... size lymphoid cells ... Smear #Peripheral #Pathology
Sebaceous hyperplasia - Yellow papule - Donut-shape - Central umbilication - Telangiectasia
Usually multiple - Causes ... #Hyperplasia #Dermatology ... #Diagnosis #Benign ... #Clinical #Photo
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
- Differential Diagnosis ... Myelofibrosis • Chronic Myeloid ... #Differential #Diagnosis ... #causes #Platelets ... #hematology
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma ... Diagnosis and Management ... osteolytic lesions and pathologic ... marrow plasma cells ... #Multiple #Myeloma
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... - Differential Diagnosis ... Formation • Multiple Myeloma ... Macrocytosis, Target Cells ... #Hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
- Differential Diagnosis ... similarly to mast cells ... Chickenpox Other Causes ... #Differential #Diagnosis ... #causes #hematology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
- Differential Diagnosis ... lymphoma, melanoma, myeloma ... #Differential #Diagnosis ... #causes #hepatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... Management Summary myelo ... = funny-shaped cells ... old, ~10,000 new cases ... Management #treatment #hematology
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