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differential management oncology clinical dermatology anemia rheumatology algorithm treatment disease hemolytic mds microscopy myelodysplastic product reactions skin smear syndrome agglutinin
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... criteria for 1) hematologic ... including peripheral blood ... myeloid cells ... NEJM Review: https
Prolymphocytes In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML). 🔬Tumor
Prolymphocytes In our case ... T-PLL) not Acute Myeloid ... 🔬Tumor cells are ... Smear #Peripheral #Pathology ... Microscopy #Clinical #Blood
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
- Differential Diagnosis ... Reactive: • Anemia/blood ... Myelofibrosis • Chronic Myeloid ... #causes #Platelets ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... - Differential Diagnosis ... Algorithm Normal Blood ... Formation • Multiple Myeloma ... #Hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
- Differential Diagnosis ... the total white blood ... similarly to mast cells ... #Differential #Diagnosis ... #causes #hematology
Tachypnea - Differential Diagnosis Framework Definitions • Tachypnea: Respiratory rate > 20/min, shallow breathing in adults •
- Differential Diagnosis ... effusion/Tamponade Hematologic ... Hypovolemic shock (blood ... • Brainstem pathology ... #Differential #Diagnosis
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... and laboratory diagnosis ... polychromatophilic cells ... hemolytic #anemia #Hematology ... #Pathology #Smear
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... Management Summary myelo ... = funny-shaped cells ... old, ~10,000 new cases ... Management #treatment #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... for secondary causes ... eosinophilia (common causes ... #Differential #diagnosis ... #hematology #eosinophilia
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
Suspected multiple myeloma ... on peripheral blood ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology ... #Diagnosis
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