58 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... criteria for 1) hematologic ... conditions - multiple myeloma ... peripheral blood myeloid ... cells NEJM Review
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... - Diagnosis and ... lymphoma, multiple myeloma ... adsorption onto cancer cells ... #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Management Summary myelo ... = funny-shaped cells ... Myelodysplastic #Syndrome ... Management #treatment #hematology
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
- Differential Diagnosis ... lymphoma, melanoma, myeloma ... Vascular: Budd-chiari syndrome ... #Differential #Diagnosis ... #causes #hepatology
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma ... Diagnosis and Management ... osteolytic lesions and pathologic ... marrow plasma cells ... #Multiple #Myeloma
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
and Associated Syndromes ... Diffuse plasma cells ... cell disorders (myeloma ... Disease #Variants #Diagnosis ... #Pathology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
- Differential Diagnosis ... Polycythemia • Multiple Myeloma ... • Budd-Chiari Syndrome ... #Differential #Diagnosis ... Algorithm #Causes #Hepatology
Herpes Zoster Mandibularis - The lesions were scattered along the area that is innervated by the
A presumptive diagnosis ... #Clinical #Photo ... #Dermatology #Herpes ... Mandibularis #Rash #NEJM
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Formation • Multiple Myeloma ... Myelodysplastic Syndromes ... Macrocytosis, Target Cells ... Algorithm #Causes #Hematology