21 results
Multiple Myeloma - Treatment Algorithm
a) Newly Diagnosed Myeloma: Transplant Eligible
b) Newly Diagnosed Myeloma: Transplant Ineligible

doi: 10.1038/s41408-020-00359-2

#Multiple
Multiple Myeloma ... - Treatment Algorithm ... a) Newly Diagnosed ... #Myeloma #Treatment ... Algorithm #management #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... thrombocytopenia, multiple ... criteria for 1) hematologic ... conditions - multiple ... cells NEJM Review
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma ... osteolytic lesions and pathologic ... marrow plasma cells ... Residency @CMC_IM #Multiple ... #Myeloma #Diagnosis
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... e.g. lymphoma, multiple ... myeloma, Waldenstrom ... #Management #treatment ... #hematology #differential
Non-cirrhotic Hyperammonemia - Differential Diagnosis Framework

Hematologic & Vascular:
 • Multiple myeloma & Acute leukemia (plasma cells
- Differential Diagnosis ... Framework Hematologic ... Vascular: • Multiple ... myeloma & Acute ... leukemia (plasma cells
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
• Suspected multiple ... myeloma, Waldenström's ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology ... #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Management Summary myelo ... = funny-shaped cells ... only curative treatment ... #Management #treatment ... #hematology #oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Formation • Multiple ... Myeloma Dysplastic ... Macrocytosis, Target Cells ... Algorithm #Causes #Hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... progress to IgM multiple ... myeloma Non-IgM ... progression to multiple ... #diagnosis #oncology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
involvement, unique or multiple ... with response to treatment ... increased IgG4+ cells ... " Treatment: ... #rheumatology