26 results
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma ... Diagnosis and Management ... osteolytic lesions and pathologic ... marrow plasma cells ... #Myeloma #Diagnosis
Multiple Myeloma - Treatment Algorithm
a) Newly Diagnosed Myeloma: Transplant Eligible
b) Newly Diagnosed Myeloma: Transplant Ineligible

doi: 10.1038/s41408-020-00359-2

#Multiple
Multiple Myeloma ... Algorithm a) Newly Diagnosed ... Eligible b) Newly Diagnosed ... -020-00359-2 #Multiple ... #Algorithm #management
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
thrombocytopenia, multiple ... myeloma, myelodysplastic ... hematologic conditions - multiple ... peripheral blood myeloid ... cells NEJM Review
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... and Management ... e.g. lymphoma, multiple ... myeloma, Waldenstrom ... adsorption onto cancer cells
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Plasmapheresis - Multiple ... myeloma / Plasmapheresis ... #Differential #Diagnosis ... #Treatment #Management
Non-cirrhotic Hyperammonemia - Differential Diagnosis Framework

Hematologic & Vascular:
 • Multiple myeloma & Acute leukemia (plasma cells
- Differential Diagnosis ... Vascular: • Multiple ... myeloma & Acute ... leukemia (plasma cells ... #Differential #Diagnosis
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
• Suspected multiple ... myeloma, Waldenström's ... myeloma is suspected ... • Unexplained pathologic ... SPEP #Hematology #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... Summary myelo ( ... = funny-shaped cells ... acute leukemia Management ... #Management #treatment
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Formation • Multiple ... Myeloma Dysplastic ... Macrocytosis, Target Cells ... #Differential #Diagnosis
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
progress to IgM multiple ... myeloma Non-IgM ... progression to multiple ... to light-chain myeloma ... Significance #hematology #diagnosis