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hematology clinical differential management microscopy algorithm leukemia radiology smear anemia causes comparison syndrome derm dermatology hemepath lymphocytic lymphoma monoclonal table
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma ... osteolytic lesions and pathologic ... marrow plasma cells ... plasma clonal cell ... #oncology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
conditions - multiple myeloma ... (12%) • giant cell ... hematopoietic stem cells ... peripheral blood myeloid ... cells NEJM Review
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... Management Summary myelo ... = funny-shaped cells ... Allogeneic stem cell ... treatment #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Rapidly rising blast cells ... : Granulocytic cells ... Hypogammaglobulinemia, smudge cells ... Leukemia #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can infiltrate ... Diagnosis: • ... smear: Smudge cells ... or basket cells ... #workup #oncology
Prolymphocytes In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML). 🔬Tumor
T-PLL) not Acute Myeloid ... 🔬Tumor cells are ... size lymphoid cells ... Smear #Peripheral #Pathology
Castleman's Disease and Associated Syndromes HYALINE VASCULAR VARIANT • unicentric, HHV8-ve, children and young. • Hyalinized vessels
disease PLASMA CELL ... Diffuse plasma cells ... disorders (myeloma ... Disease #Variants #Diagnosis ... #Pathology
Comparison of basophils and mast cells (in bone marrow). #Basophils #MastCells #Pathology #Marrow #Smear #Microscopy #Comparison #Table
basophils and mast cells ... Basophils #MastCells #Pathology ... Table #Clinical #Diagnosis
Primary Bone Tumors - Differential Diagnosis Algorithm Metastatic - Most common tumour in adults - Breast
- Differential Diagnosis ... Non-Malignant • Giant Cell ... tumours • Multiple Myeloma ... #Differential #Diagnosis ... Orthopedics #Causes #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood cells ... , or all three myeloid ... , and the cells ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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