10 results
Differential Diagnosis of Syncope
First, is it syncope? History is very important for distinguishing syncope from other
Differential Diagnosis ... Ask about precipitating ... #Diagnosis #EM # ... Neuro #IM #Sycope ... #Algorithm #Ddxof
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Identification of onset (acute ... 2) Presence of symptoms ... #EM #IM #Nephro ... #Differential #Algorithm ... #Ddxof
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... are not caused ... anterior/posterior MSK
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... - ACS, AKI, acute ... Lysis of tumor cells ... #TLS #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Release from blast cells ... : >3 symptoms, or ... management #hematology #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Algorithm Hodgkin ... pattern of spread, B symptoms ... Treated Like Acute ... Amy Chung, MD, MSc ... Classification #pathophysiology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Leukemia #Hematology #Oncology ... #Diagnosis
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
clinical findings Acute ... hearing loss, nausea ... #Mastoiditis #pathophysiology ... #signs #symptoms ... #diagnosis #otology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... (GBS) Acute autoimmune ... than one after symptom ... the underlying pathophysiology ... Hospital of Baltimore IM
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis

EPIDEMIOLOGY:
PFAPA is the most common syndrome entailing
fever (FMF) PATHOPHYSIOLOGY ... : The exact cause ... ), - Muckle–Wells ... known pathogenic cause ... #Diagnosis