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diagnosis hematology causes hemolytic leukemia management workup chronic classification lymphocytic agglutinin apml cold crisis curve dehydrogenase differentiation disease dissociation elevated
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Diagnosis Algorithm ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... or λ), Smudge Cells
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... ALL Symptoms: ... - infiltrates (anemia ... ) CLL Symptoms: ... Leukemia #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... lymphoproliferative disorders ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... diagnosis #workup #oncology
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
- Differential ... Diagnosis Algorithm ... • Peripheral blood ... DAT (-) → Sickle Cell ... #Differential #
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
of anemia include ... Immunoglobulin M (IgM) • Blood ... younger pts) Differential ... sensitize red blood ... cells (RBCs) at
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... age 70 years Symptoms ... cell count (anemia ... count with differential ... diagnosis #hematology #oncology
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
disorder. ... These cells can ... The underlying pathophysiology ... of the baseline anaemia ... Features #Signs #Symptoms
Oxyhemoglobin Dissociation Curve Left Shift - decreased unloading of O2 at tissue level (i.e. increased
• stored red blood ... cells - Hb variant ... anemia #Oxyhemoglobin ... Dissociation #Curve #Pathophysiology ... #Right #Shift #Differential
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Diagnosis Algorithm ... Normal Blood Smear ... • Small Bowel Disorder ... Macrocytosis, Target Cells
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... proportion of the red blood ... cells. ... experience some symptoms ... three peripheral blood
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