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diagnosis management nephrology aids als amyotrophic apml associated causes cord dementia differentiation disorder disorders gitelman hand headache hematology hypokalemia lateral
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
Diagnosis Algorithm ... papilledema • Horner syndrome ... history of cancer, HIV ... ) • Systemic symptoms ... #neurology #PHANTOMS
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
dementia Pathophysiology ... CNS ○ Infected cells ... • Depressive symptoms ... The clinical syndrome ... dementia #AIDS #Neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Cord Disorders - Differential ... , HIV, CMV, HTLV ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology ... #algorithm
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Infection - Viral (HIV ... : • Triad of symptoms ... urine • Other symptoms ... kidney tubular cells
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... initiation • Differential ... • Steroids: IV
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... fasciculations Common Symptoms ... conditions listed in differential ... motor neurons - IV ... Lateral #Sclerosis #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Presentation: Systemic Symptoms ... affects the skin, neurologic ... • Progressive symptoms ... cognitive impairment, neurologic
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
apical membrane of cells ... Muscle weakness, dizziness ... ratio 0.5%) Differential ... #diagnosis #nephrology ... #management #pathophysiology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Bilateral signs and/or symptoms ... simplex virus, HIV ... diagnosis #management #neurology ... #differential
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