6 results
Esophageal Crohn's Disease Management Algorithm

Assess for Active Symptoms and for Stricturing/Fistulizing Disease
Stricturing DX:
 • Bx r/o
Management Algorithm ... Assess for Active Symptoms ... SEMS • PEG w/ EN ... Endo • Anti-TNF ... #Management #Algorithm
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... + lab signs of end ... : • Pathophysiology ... Lysis of tumor cells ... TLS #diagnosis #management
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
in SBP > 40 - End-organ ... , Severe Valve Disease ... Abdominal compartment syndrome ... #criticalcare #algorithm ... #treatment #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Fibrinolysis → End ... Schistocytes, helmet cells ... • Severe Liver Disease ... causes #treatment #management
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
multicentric Castleman disease ... , Lyme disease, ... cell lymphoma Pathophysiology ... and the systemic symptoms ... TAFRO #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... ▪ Autoimmune diseases ... Common Signs and Symptoms ... Pathophysiology