47 results
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... Anemia - Giant cells ... neurological findings #GiantCell ... Temporal #Arteritis #Pathophysiology ... #Symptoms #Vasculitis
Giant Cell Arteritis (GCA) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines
 • Visual Symptoms/Loss or
Arteritis (GCA) - Vasculitis ... Management Algorithm ... Without Visual Symptoms ... @MithuRheum #GiantCell ... #Management #Treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... #diagnosis #management
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
syndromes such as ... Signs and symptoms ... stimulation Clinical ... sclerosis #diagnosis #management ... #neurology #treatment
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... gene mutated in all ... cells -> Mutagenic ... Retinoblastoma #pathophysiology ... #symptoms
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
Pathogenesis and Clinical ... various inflammatory cells ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Pathogenesis and Clinical ... vascular endothelial cells ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Emphysematous Cystitis
Epidemiology:
 • Usually middle-aged diabetic women
 • Other RF: neurogenic bladder, urinary tract outlet obstruction,
immune compromise Clinical ... Signs/Symptoms: ... Pathophysiology: ... Coli, but can also ... data • Early treatment
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
pattern of spread, B symptoms ... not as common ... Responsive to Treatment ... Amy Chung, MD, MSc ... Classification #pathophysiology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Diagnosis and Management ... poor nutrition Clinical ... and tachypnea As ... nonimmune hemolysis MSK ... Treatment: