10 results
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Differential Diagnosis Algorithm ... Transcellular Shift Into Cells ... imports K+ into cells ... causes #potassium #low ... #pathophysiology
How dendritic cells (DCs) orchestrate adaptive immunity
1- Sensing of microbial and damage signals by DCs
2- Phenotypic
How dendritic cells ... adaptive #immunity #immunology ... #pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... Lymphocyte - 5% RS cells ... (LP) tumour B cells ... B-Cell ~90% • Low ... Classification #pathophysiology
Approach to Hypomagnesemia 

Fractional excretion of magnesium = (urine magnesium x serum creatinine)/ [0.7 (serum magnesium
magnesium into cells ... Hypomagnesemia #algorithm ... diagnosis #causes #nephrology ... #magnesium #low
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... Decreased Intake: • Low ... smooth muscle cells ... #Pathophysiology ... #Nephrology #Chloride
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... Physiology: CO2: • Low ... water leaves brain cells ... Pressure #ICP #Pathophysiology ... #neurology #neurosurgery
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
of phase 4 to slow ... ++ influx into cells ... inotropy) ACCP Cardiology ... Classification #Classes #pathophysiology ... #cardiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
increases out of cells ... ++ influx into cells ... inotropy) ACCP Cardiology ... Classification #Classes #pathophysiology ... #phases #cardiology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... invades mononuclear cells ... CNS ○ Infected cells ... ARVs can have low ... untreated HIV and with low
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
apical membrane of cells ... alkalosis • Normal or low ... Syndrome #diagnosis #nephrology ... #management #pathophysiology