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diagnosis symptoms neurology differential syndrome vasculitis hematology hemophagocytic hlh lymphohistiocytosis treatment agammaglobulinemia algorithm allergy als amyotrophic anaphylaxis arteritis asthma benign
Inflammatory mechanism of asthma. Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... These T cells then ... TH2 cells also migrate ... #asthma #pathophysiology ... immunology
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... Natural Killer Cells ... cell activity #Inflammatory ... #Inflammation #pathophysiology ... #immunology
Anaphylaxis: Pathogenesis Anaphylaxis is a Type 1 hypersensitivity reaction While the primary mechanism of anaphylaxis is mast cell
production of inflammatory ... Recruitment of inflammatory ... cells • ANS activation ... #Anaphylaxis #pathophysiology ... #immunology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
allergen-specific plasma cells ... complexes bind to mast cells ... cells recruited ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
maturation of B cells ... from precursor cells ... Absence of mature B cells ... CD19+) and plasma cells ... #immunology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
mutation) that alter inflammatory ... yrs old; F>M Signs ... Anemia - Giant cells ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
the mastoid air cells ... and mastoid air cells ... : Extension of inflammatory ... #Mastoiditis #pathophysiology ... #signs #symptoms
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
Bell's Palsy - Diagnosis ... ophthalmoplegia), systemic signs ... sarcoid or other CNS inflammatory ... within 4m #Bells ... #Treatment #Neurology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... cytokines -> localized inflammatory ... removal of these cells ... Manifestations #pathophysiology ... #diagnosis #signs
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
activating cellular inflammatory ... vascular endothelial cells ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs
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