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diagnosis symptoms differential management neurology allergy als amyotrophic arteritis complications giantcell henochscholeinpurpura hsp hypersensitivityreaction iga lateral lupus manifestations mucocutaneous myelitis
Inflammatory mechanism of asthma. Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
of asthma. ... Airway epithelial cells ... These T cells then ... #asthma #pathophysiology ... immunology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
mutation) that alter inflammatory ... yrs old; F>M Signs ... Anemia - Giant cells ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
allergen-specific plasma cells ... complexes bind to mast cells ... cells recruited ... Complications: • Acute Asthma ... #pathophysiology
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
activating cellular inflammatory ... vascular endothelial cells ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... cytokines -> localized inflammatory ... removal of these cells ... Livedo Reticularis, Vasculitis ... #diagnosis #signs
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... attraction of various inflammatory ... cells to the area ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Microglial cells ... are the immune cells ... can become pro-inflammatory ... between nerve cells
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... purpura: Strong sign ... Multinucleated giant cells ... Eosinophilia, asthma ... syndrome: Ocular inflammatory
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Overview Focal inflammatory ... monophasic Pathophysiology ... • Bilateral signs ... Pleocytosis > 100 cells ... - Sjogren - Vasculitis
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