10 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Pathophysiology ... Campylobacter jejuni - HIV ... Diagnosis: • ... #Syndrome #diagnosis ... #neurology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... : 2 hit mechanism ... : 33% • Treatment ... #hematology #diagnosis ... #comparison #table
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... immunodeficiency virus (HIV ... the underlying pathophysiology ... and cauda equina TREATMENT ... #management #neurology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
natural killer cells ... erythematosus Type IV ... Classification #Pathophysiology ... #Allergy #Diagnosis ... #Reactions #Table
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... Diagnosis: MRI ... Treatment: • HAART ... treatment • Cognitive ... dementia #AIDS #Neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
of HIV/AIDS patients ... increase in CD4+ cells ... superinfection, drug reactions ... albicans • Epstein Barr ... : • Drug reaction
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Elimination (see Table ... Drives K+ into cells ... #Hyperkalemia #Diagnosis ... #potassium #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Infection - Viral (HIV ... kidney tubular cells ... per day until stable ... #nephrology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Microglial cells ... column Treatment ... motor neurons - IV ... Lateral #Sclerosis #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Pleocytosis > 100 cells ... simplex virus, HIV ... Transverse Myelitis Treatment ... #management #neurology