13 results
Bell's Phenomenon on Physical Exam

Carles Bell realized that when trying to close the eye on the
Bell's Phenomenon ... neurologiabr #Bells ... #Phenomenon #Sign ... #PhysicalExam #ophthalmology ... #neurology
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
& inflammatory cells ... exertion • Neurologic ... : Bell's palsy, ... dysrhythmias • Ophthalmologic ... Diagnosis #Symptoms #Signs
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... Anemia - Giant cells ... neurological findings #GiantCell ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... Retinoblastoma Signs ... / Symptoms / Complications ... #ophthalmology ... #diagnosis #signs
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
Otitis Media: Complications ... to mastoid air cells ... becomes more severe Signs ... #pathophysiology ... #symptoms #signs
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
B and CD-4+ T cells ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... removal of these cells ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
- Microglial cells ... of UMN and LMN signs ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
diffusion of K+ out of cells ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Retina • Ganglion cells ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... #diagnosis #signs