22 results
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Immune Reactions ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology ... #immunology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Inflammatory mechanism of asthma ... These T cells then ... induce B-cell class ... #asthma #pathophysiology ... #inflammatory #immunology
Innate Immune Cells - Pathophysiology
The innate immune system consists of granulocytes, mast cells, natural killer cells,
Innate Immune Cells ... - Pathophysiology ... antigens on MHC class ... #Pathophysiology ... #immunology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
- Mechanism of Action ... Allergen-specific lgE causes ... allergies, Eczema, Asthma ... - Mechanism of Action ... T-cells recruit
Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 • Slows depolarization
Classification Class ... depolarization in fast AP cells ... depolarization in slow AP cells ... Blockade • Prolongs action ... #cardiology #pharmacology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #pathophysiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
, Intermediate Action ... Blockade, Fast Action ... ++ influx into cells ... Vaughan #Williams #Pharmacology ... #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
exposure to allergen causes ... harmful -> Th Cells ... macrophages, mast cells ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... , Intermediate Action ... Blockade, Fast Action ... Antiarrhythmics #Pharmacology ... #pathophysiology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
similarly to mast cells ... allergic reaction or asthma ... Or Inflammatory Reactions ... ’s Disease • Asthma ... Chickenpox Other Causes