24 results
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
is caused by many ... release from mast cells ... DrugInduced #Edema #Medication ... #Pharmacology # ... Pathophysiology
Therapy for AL Amyloidosis 2019 
 - Antibodies (Plasma cells) 
 - Proteasome Inhibitors 
 -
Antibodies (Plasma cells ... ALAmyloidosis #Therapy #Medications ... #Therapies #Pharmacology ... #Management #Classes
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
anti-diabetic medications ... kidney), which causes ... SGLT2 #Inhibitors #Pharmacology ... #Medications #DM2 ... #Diabetes #Endocrinology
Bisphosphonates for Osteoporosis Treatment or Prevention 

Bisphosphonates are common medications used in the treatment and prevention
Bisphosphonates are common medications ... There are 4 drugs ... Schedule #Frequency #Pharmacology ... #Endocrinology ... #Osteoporosis #Management
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Inhibitors Increasing Indications ... Significant Adverse Drug ... level < 200 mg/dL Pathophysiology ... EuDKA #diagnosis #management ... #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
thing about this drug ... This drug class ... Renal #Dosing #Pharmacology ... #Management #Diabetes ... #DM2 #Endocrinology
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
The gout drug pegloticase ... Homeostasis #Gout #Pathophysiology ... #Pharmacology # ... Medications #Management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... Dyskeratosis congenita • Drugs ... - Cytotoxic drugs ... - Antithyroid medications ... hematology #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Activation of CD8 T cells ... immune deficiency, Drugs ... , Unknown cause ... Lymphohistiocytosis #diagnosis #management
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... pachydermoperiostosis, drugs ... or refractory cases ... #Endocrinology ... #Treatment #Pathophysiology