9 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... Differential Diagnosis: Infection ... sepsis), PE, DAH, CHF ... diagnosis #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... mass • Rapidly rising ... -> AML: Blast crises ... smear: Blasts APML ... #Leukemia #Hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... uncovered incidentally during ... for secondary causes ... glucocorticoid treatment ... Differential #diagnosis #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
pathogens, including PML ... less than 200 cells ... Antimicrobial treatment ... Demyelinating disease caused ... - Generally >3 cm
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... Myelogenous Leukemia (CML ... • Parvovirus infection ... factors (examples: G-CSF ... Syndromes #diagnosis #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Vascular Causes ... syndrome, Congestion/CHF ... Liver Injury: • Infectious ... HEV, EBV, HSV, CMV ... #hepatology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
if SSTI or port infection ... abdominal pain; full infectious ... syndrome): - Hematologic ... Treat underlying cause ... “big & sticky” cells
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
the determined cause ... #differential #algorithm ... #management #cardiology ... #heartfailure #chf ... icu #clinical #pharmacology
A quick infographic on the importance of sun protection and the various results of sun damage
#wavelengths #causes ... #diagnosis #dermatology ... Toxicol Appl Pharmacol ... Mechanisms and treatments ... Dong K, Goyarts