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diagnosis differential oncology management causes leukemia workup classification dermatology lymphomas rheumatology acuteleukemia allergy amyloid amyloidosis anemia basophilia basophils blood bloodcells
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... (Chronic Myeloid ... (Chronic Lymphocytic ... #Leukemia #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... can indicate disease ... lymphoproliferative disorders ... #Chronic #Lymphocytic ... workup #oncology #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Differential Diagnosis Algorithm ... - CD7, CD3 Chronic ... • Lymphoid (CLL ... or λ), Smudge Cells ... #hematology #Markers
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... leukemia in adults • Disorder ... chemotherapy for low-risk disease ... #Chronic #Lymphocytic ... Leukemia #oncology #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... Differential Diagnosis Algorithm ... Lymphoproliferative #Disorders ... pathophysiology #Hematology ... #differential #algorithm
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... to impaired B-cell ... Granulomatous lymphocytic ... hypogammaglobulinemia #immunology ... #hematology #diagnosis
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Differential Diagnosis Algorithm ... Neoplastic / Hematologic ... Obstructive Pulmonary Disease ... Myasthenia Gravis Pharmacologic ... • Somatization Disorder
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
similarly to mast cells ... Myeloproliferative Disorders ... : • Chronic myeloid ... Colitis and Crohn’s Disease ... Diagnosis #causes #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... • Sickle cells ... Consider sickle cell ... Consider RBC membrane disorder ... #workup #hematology
The hematopoietic tree and the resulting leukemias and lymphomas The hematopoietic tree refers to the hierarchical
differentiate into all ... are malignant disorders ... abnormal growth of lymphocytes ... on the rate of disease ... Chronic leukemias
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