11 results
Mechanisms of thiazide diuretic side effects

Dr. Muner Mohamed @MunerMohamed1

#thiazide #diuretic #pharmacology #pathophysiology #sideeffects #adverseeffects #nephrology
Mechanisms of thiazide ... #diuretic #pharmacology ... #pathophysiology ... #sideeffects #adverseeffects ... #nephrology
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
Diuretic Electrolyte ... Excretion Effects Diuresis ... , Uric Acid - Thiazide ... electrolytes #effects #pharmacology ... #comparison #table
Pharmacology of diuretics

Acetazolamide, Loop diuretics, Thiazide‐like diuretics, MRA, Amiloride

Site of Action, Maximum Dose, Half-Life, Onset, Bioavailability,
Pharmacology of ... , Thiazide‐like ... #Pharmacology # ... Comparison #Table ... #Dosing #Loop #Thiazide
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... furosemide) 4) Thiazides ... Adenosine #Nephron #Pathophysiology ... #Action #nephrology ... #pharmacology
Mechanism of Action of Diuretics
Amiloride, Triamterene, Spironolactone
Loop Diuretics
Thiazides
Acetazolamide

#Diuretics #Mechanism #Action #pharmacology #pathophysiology #nephrology
Thiazides Acetazolamide ... #Diuretics # ... Mechanism #Action #pharmacology ... #pathophysiology ... #nephrology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... Ethacrynicacid THIAZIDES ... #Medications #Pharmacology ... #summary #table ... #nephrology
Pharmacokinetics of commonly used diuretics medications in CKD, Cirrhotic Ascites, and Heart Failure
 • Furosemide
 •
commonly used diuretics ... Spironolactone MCW Nephrology ... #pharmacology # ... Pharmacokinetics #halflife #comparison ... #table
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... Symport (Loop Diuretics ... +CI- Symport - Thiazide ... #Nephrology #Pharmacology ... #Medications #Table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
G-K), K-sparing diuretics ... Elimination (see Table ... Drives K+ into cells ... ± thiazide / acetazolamide ... Treatment #potassium #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
apical membrane of cells ... diuretic abuse ... Surreptitious diuretic ... Syndrome #diagnosis #nephrology ... #management #pathophysiology