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diagnosis management causes antibiotics hypokalemia neurology algorithm apml chloramphenicol daptomycin differentiation druginduced edema encephalopathy fever gitelman hematology hypoxemia hypoxia immune
Daptomycin - Antibiotics Class Overview Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Antibiotics Class Overview ... and depolarizes cells ... cidal nature) #Pharmacology ... #Antibiotics #Review ... #Overview #Daptomycin
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Hypokalemia - Differential ... imports K+ into cells ... - Refeeding Syndrome ... #Hypokalemia #Differential ... potassium #low #pathophysiology
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Refeeding Syndrome ... Overview What ... • Nephrotic syndrome ... #Nutrition #Differential ... #Diagnosis #Pathophysiology
Hypoxia and Hypoxemia - Overview Hypoxia - insufficient oxygen delivered to tissues to meet demands Hypoxemia - low
and Hypoxemia - Overview ... CYTOPATHIC HYPOXIA - Cells ... summary #pulmonary #differential ... diagnosis #causes #pathophysiology
Drug-Induced Edema Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
release from mast cells ... Medication #Causes #Differential ... #Pharmacology # ... Pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Encephalopathy Syndrome ... (PRES) Overview ... Clinico-Radiological Syndrome ... Etiology: • Pathophysiology ... Reversible course Differential
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Release from blast cells ... initiation • Differential ... Differentiation #Syndrome
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Overview Epidemiology ... SLE • Mikulicz syndrome ... lubricants • Pharmacologic ... #Sjogrens #Syndrome
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis Overview ... monophasic Pathophysiology ... Pleocytosis > 100 cells ... management #neurology #differential
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... Overview What ... apical membrane of cells ... ratio 0.5%) Differential ... nephrology #management #pathophysiology
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