17 results
hematology differential management causes clinical emergencies leukemia mds myelodysplastic oncologic acidosis anemia apml ascites blastic bradyarrhythmia bradycardia cancer cd4 chestpain
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... = funny-shaped cells ... Allogeneic stem cell ... treatment #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
hematopoietic stem cells ... number of CD34+ cells ... cellularity + dysplastic cells ... number of CD34+ cells ... Number of CD34+ cells
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can infiltrate ... smear: Smudge cells ... or basket cells ... aplasia • ITP ... #workup #oncology
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) • Plasmacytoid Dendritic Cells (pDC) Neoplasms • BPDCN • BPDCN
Blastic Plasmacytoid ... Dendritic Cell ... Plasmacytoid Dendritic Cells ... #Neoplasm #diagnosis ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood cells ... Causes • Anemia • Aplastic ... , and the cells ... #diagnosis #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
lymphadenopathy • Blast cells ... Rapidly rising blast cells ... : Granulocytic cells ... Leukemia #Hematology #Oncology ... #Diagnosis
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential Diagnosis ... Hyperviscosity Syndrome ... neutrophil count < 500 cells ... : Tumor Lysis Syndrome ... #differential #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Release from blast cells ... • Induce blast cell ... Differentiation #Syndrome ... management #hematology #oncology
LUMBAR Syndrome What do you call a segmental lumbosacral hemangioma + spinal problems?? LUMBAR syndrome, a fairly
LUMBAR Syndrome ... What do you call ... LUMBAR syndrome, ... + MRI/MRA abd/pelvis ... #Radiology #Diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... capillary leak syndrome ... Thrombosis in vascular beds-renal ... #Differential #Diagnosis ... #Oncology
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