14 results
diagnosis oncology syndrome disease hemeonc hemophagocytic hlh lymphohistiocytosis adultonset anemia aplastic apml arthritis causes chronic classification cll coagulation dermatology dic
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... • Pulmonary: pleural ... effusion, infiltrates ... Disease #diagnosis #management ... #treatment #rheumatology
MCP Synovitis on Ultrasound Young rheumatology patient. Florid synovitis of the MCP joint with effusion on dynamic
Ultrasound Young rheumatology ... Synovitis #Metacarpal #MSK ... #Ultrasound #POCUS ... #Clinical #Joint ... #Effusion
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 Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
nodules, joint effusions ... Ultrasound Diagnosis: CLINICAL ... exam and imaging Treatment ... Arthritis #diagnosis #management ... #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... HoTN, edema and effusions ... APML #diagnosis #management ... #hematology #oncology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Related Disease Clinical ... increased IgG4+ cells ... " Treatment: ... Disease #diagnosis #management ... #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
lymphocytes, smudge cells ... immunophenotype Clinical ... transformation) Treatment ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
ducts Clinical ... thickening or effusion ... phenomenon (16%) MSK ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... number of CD34+ cells ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... Schistocytes, helmet cells ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
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