43 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... = funny-shaped cells ... old, ~10,000 new cases ... only curative treatment ... #treatment #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... thrombocythemia), Autoimmune disease ... adsorption onto cancer cells ... Syndrome #Diagnosis #Management ... #treatment #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... with established disease ... normal in mild cases ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Drugs, Unknown cause ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia is usually caused ... Then, ask 3 questions ... the underlying cause ... vaptans (HF/liver disease ... #management #nephrology
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
an autoimmune disease ... antibodies - MuSK-positive ... More likely to cause ... glucocorticoids - can cause ... Gravis #diagnosis #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... : symptomatic treatment ... • Severe disease ... DRESS #Syndrome #dermatology ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Severe Liver Disease ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
lymphocytes, smudge cells ... transformation) Treatment ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Smoking Cessation and Nicotine Replacement Therapy (NRT)
Smoking is the leading cause of preventable death and a
is the leading cause ... multiple cancers, CV disease ... Cessation • Ask ... #Therapy #NRT #management ... #treatment