20 results
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
warriors") • Acute ... pre-determined etiology Signs ... TendonRupture #diagnosis #signs ... #symptoms #pathophysiology ... #msk #orthopedics
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... B and CD-4+ T cells ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Cryptogenic Organizing Pneumonia - Illness Script

PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... Males=Females SIGNS ... /SYMPTOMS: • Acute ... , neoplastic) TREATMENT ... TylerLarsenMD #COP
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Classic - Nodular Sclerosis ... pattern of spread, B symptoms ... Treated Like Acute ... Amy Chung, MD, MSc ... Classification #pathophysiology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
Summary Overview: chronic ... knees, shoulders Signs ... & Symptoms: • ... exam and imaging Treatment ... ideally limit for acute
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... - ACS, AKI, acute ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Pathophysiology ... of UMN and LMN signs ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
vasoconstrictive • Acute ... Stage 2: Moderate/sclerotic ... #Retinopathy #pathophysiology ... ophthalmology #diagnosis #signs ... #symptoms #complications
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
The underlying pathophysiology ... 2) Aplasia - Acute ... patients with co-existent ... Crisis #Features #Signs ... #Symptoms