114 results
diagnosis symptoms treatment syndrome clinical pharmacology complications msk neurology pocus rheumatology algorithm cardiology classification differential disease hematology immunology summary causes
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
smoking, etoh, decr activity ... #Osteoporosis #pathophysiology ... #signs #symptoms
Gaucher Disease Pathophsiology • Lysosomal storage disorder • Deficiency of ß-glucocerebrosidase • Accumulation of glucosylceramide in macrophages Diagnosis
Gaucher Disease Pathophsiology ... ß-glucocerebrosidase activity ... Disease #Diagnosis #Signs
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Diagnosis and Management ... cases Clinical Signs ... years - May have signs ... /symptoms of active ... decreased reflexes Pathophysiology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Excessive glutamate activity ... of UMN and LMN signs ... by decreasing activity ... neurology #diagnosis #management
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... Anemia - Giant cells ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
and activate them ... or plasma cells ... neutralizing them - Activate ... Complement: Abs activate ... Humoral #Immunity #pathophysiology
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Natural Killer Cells ... cytotoxic cell activity ... #Inflammation #pathophysiology
Candidates for Medical Treatment of Ectopic Pregnancy with Methotrexate - Hemodynamically stable - No
fetal cardiac activity ... on ultrasound examination ... Ectopic #Pregnancy #Management
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... removal of these cells ... decr release and activity ... Manifestations #pathophysiology ... #diagnosis #signs
Inflammatory mechanism of asthma. Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... antigens and thereby activate ... naive CD4 T cells ... These T cells then ... #asthma #pathophysiology
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