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management diagnosis cascade medications doac druginduced pathophysiology sle syndrome warfarin algorithm anticoagulant anticoagulants apixaban behcets bloodproduct cardiology causes chemotherapy clot
Diagram demonstrating TEG (thromboelastography) variables as they relate to the coagulation cascade. Dr. Wells Brambl @DoctorWellsMD #TEG #thromboelastography
relate to the coagulation ... Wells Brambl @DoctorWellsMD ... thromboelastogram #coagulation ... #cascade #anticoagulation ... #laboratory #hematology
Coagulation Cascade and Anticoagulant Sites of Action - Amy Chung, MD, MSc https://twitter.com/AmyChung #AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... twitter.com/AmyChung #AntiCoagulation ... #Medications #Pharmacology ... Mechanisms #DOAC #Hematology
Managing warfarin INR Warfarin dosage must be individualized according to the patient's response to the drug, and
Over-anticoagulation ... hemorrhage, while under-coagulation ... #treatment #medications ... #table #pharmacotherapy ... decisionaid #cardiology #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... and endothelial cells ... #Coagulation #Cascade ... diagnosis #models #hematology ... pathophysiology #anticoagulation
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... immunosuppressive meds • +/- Anticoagulation ... #management #pharmacology ... #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... Schistocytes, helmet cells ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... constitutional symptoms • Treatment ... life-threatening • Treatment ... sle #comparison #table ... #rheumatology #
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
not “packed” red cells ... Packed red cells ... proteins, all coagulation ... Contents #Volume #Hematology ... #Management #Table
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... Chemotherapy #Oncology #Hematology ... #Interactions #Table ... #Pharmacology
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
Induced Systemic Lupus ... for 1 year of treatment ... SLE #Systemic #Lupus ... medications #drugs #pharmacology ... differential #diagnosis #rheumatology
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