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diagnosis liver algorithm injury transaminitis aflp causes chemistry classification common comparison cvid dili drug gastroenterology hellp hepatocellular hodgkins hypogammaglobulinemia icp
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
, Toxic Hepatitis ... 2-5x normal - Hemolysis ... Liver #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... • Cholestatic disease ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... HELLP, Celiac disease ... #Diagnosis #hepatology ... Transaminitis #LFTs ... #hepatitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... of cholestatic disease ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... symptoms of liver disease ... Idiosyncratic #differential ... gastroenterology #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Chronic viral hepatitis ... liver #injury #hepatitis ... #differential # ... diagnosis #algorithm #hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... HELLP Syndrome (Hemolysis ... #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and hepatitis ... and autoimmune hemolytic ... and M panel Management ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... Immunohistochemical studies (to differentiate ... number of sites of disease ... classification #hematology ... #oncology #management
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