10 results
Map of proliferative blood disorders. 

By Ariella Coler-Reilly @ariellastudies

#Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
ariellastudies #Algorithm ... blood #disorders #leukemia ... #hematology #oncology ... #diagnosis #CML ... #CLL #AML #Map
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
: ALL, CML, AML, ... APML, CLL Acute ... ↓ LAP Score • CML ... -> AML: Blast crises ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
incompetent • CLL ... Transform to DLBCL, PML ... leukemia #CLL ... diagnosis #workup #oncology ... #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Differential Diagnosis Algorithm ... • EBV • CMV ... #Causes #Hematology ... #Oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
involved) • No leukemic ... Malignancies (eg CML ... , ALL) • Solid ... NonHodgkins #comparison #oncology ... #differential #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... lymphadenopathy more diffuse ... Treated Like Acute Leukemias ... relapse - Amy ... pathophysiology #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... transformation to AML ... (CML) • Felty ... progression to AML ... #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... stenting - Consider anticoagulation ... Usually myeloid leukemias ... fluids (200–300 mL ... : - Seen with AML
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
generally requires all ... PV, MDS, CML) Treatment ... transformation into MDS or AML ... • Treatment algorithms ... Hydroxyurea + anticoagulation
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
current treatment algorithm ... acute myeloid leukemia ... (AML). ... cytopenias and AML ... #algorithm #hematology