8 results
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Disorders of Pigmentations ... sclerosis (white "ash ... versicolor (more commonly ... #skin #dermatology ... #causes
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... Internal organs Most common ... Causes: - Idiopathic ... , breast CA - Hematologic ... #oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Malignancy (e.g. hematologic ... ) • Endocrine disorders ... pancreatitis, protein-losing ... vein thrombosis Hematologic ... Kidney disease common
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... to impaired B-cell ... DDX - Other causes ... Burns • Protein-losing ... hypogammaglobulinemia #immunology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Most common cytopenia ... Neutropenia • Platelet Disorders ... Syndromes #diagnosis #hematology ... #oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... • Autoimmune disorders ... (NSHL) - (most common ... classification #hematology ... #oncology #management
PALM RASHES 
Common features and patterns:
1.	Color:
o	Red or erythematous: Common in inflammatory or allergic reactions.
o	Purple or purpuric:
suggest vascular or hematologic ... depigmentation disorders ... o Moist or oozing ... Seen in systemic causes ... disease. 6 Causes
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... thrombocytosis, only other commonly ... hemoproliferative disorder ... • Treatment algorithms ... Thrombocythemia #ET #hematology