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diagnosis differential hemolysis intravascular management microcytic normocytic oncology aafp atlas classification common cvid folate folicacid hodgkins homocysteine hypogammaglobulinemia immunodeficiency immunology
Evaluation of Patients with Anemia Microcytic, Normocytic, Macrocytic, Hemolytic (Intravascular and Extravascular) #Diagnosis #Anemia #Workup #Macrocytic #Microcytic #Normocytic
Patients with Anemia ... , Macrocytic, Hemolytic ... and Extravascular ... #Workup #Macrocytic ... #Differential #Algorithm
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... anemia): ... ) (e.g. lupus, CLL ... #diagnosis #hematology ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Diagnosis Algorithm ... • Sickle cell ... anemia • ... #Causes #Hematology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Algorithm and Causes ... #Hemolytic #Anemia ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Differential Diagnosis Algorithm ... Polychromatic Macrocytes ... Bleed • Hemolysis ... #Causes #Hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... 95 (or 100) is macrocytic ... acute blood loss, hemolysis ... #Workup #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Lead poisoning • Macrocytic ... spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... , Disseminated intravascular ... #differential #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Differential Diagnosis Algorithm ... DAT (-) → Sickle Cell ... & microcytic RBCs ... #causes
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... evaluation of macrocytic ... Hemorrhage or hemolysis ... the most likely cause ... #Workup #AAFP
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Consider sickle cell ... #Anemia #Differential ... #workup #hematology
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