10 results
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
and Pathophysiology ... 1) Na/K ATPase ... Pump - Digoxin works ... intracellular calcium causes ... - Hyperkalemia (
Causes of Hypokalemia - Differential Diagnosis Algorithm
Once pseudohypokalemia is ruled out, causes of hypokalemia can be
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... discrete buckets: 1. ... #Causes #workup ... #nephrology
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Hypokalemia Differential ... Algorithm Acidosis ... #Differential #Algorithm ... #Diagnosis #Causes ... #Workup #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
recessive salt-losing ... prevalence of 1- ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... #nephrology #diagnosis
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm
Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... antagonism • alpha-1 ... agonism • Digoxin ... IntercellularShift #Nephrology ... #Causes
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
Causes of Secondary ... (correction of hypokalemia ... Oral sodium loading ... syndrome - Overnight 1- ... #Screening #Workup
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... +K / serum Na >1 ... : Hypovolemia, Hypervolemia ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Calcineurin inhibitors, Digoxin ... reabsorption) Workup ... only if no clear cause ... 5-10U reg IV + 1- ... Treatment #potassium #nephrology
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
Cooling jackets ... boluses 10 ml.kg-1 ... with dantrolene Hyperkalaemia ... hyperventilate, sodium ... Diagnosis #Management #Workup
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
• Prevalence: 1- ... 2 cases per million ... Person Syndrome Pathophysiology ... antibody that works ... others (botox, sodium