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diagnosis differential high hypokalemia management anesthesia anesthesiology cardiology checklist classification crisis hyperthermia intercellularshift intraoperative k malignant pathophysiology pharmacology treatment
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pathophysiology 1) ... works by directly ... intracellular calcium causes ... - Hyperkalemia ( ... , in states of hypokalemia
Causes of Hypokalemia - Differential Diagnosis Algorithm Once pseudohypokalemia is ruled out, causes of hypokalemia can be
Causes of Hypokalemia ... discrete buckets: 1. ... (low intake) 2. ... #Causes #workup ... #nephrology
Hypokalemia Differential Algorithm Acidosis - RTA - Diarrhea pH Normal 1. Decreased Mg 2. Intracellular Shift
Hypokalemia Differential ... Algorithm Acidosis ... #Differential #Algorithm ... #Diagnosis #Causes ... #Workup #Nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... acidosis (type 1 ... of 2), Ureterosigmoidostomy ... #causes #nephrology ... #potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
: • Digoxin ... Increased K Intake: 1. ... Medications 2. ... differential #diagnosis #causes ... #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
: • Digoxin ... Increased K Intake: 1. ... Medications 2. ... differential #diagnosis #causes ... #nephrology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... Resistance • Beta-2 ... antagonism • alpha-1 ... agonism • Digoxin ... IntercellularShift #Nephrology
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... Digoxin and related ... the epithelial sodium ... the epithelial sodium ... Diagnosis #High #Potassium
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Calcineurin inhibitors, Digoxin ... reabsorption) Workup ... only if no clear cause ... 5-10U reg IV + 1- ... #nephrology #K
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia Unexplained increase in ETCO2 AND tachycardia AND increased
other, more common causes ... (see 2-8 Peri-operative ... boluses 10 ml.kg-1 ... with dantrolene Hyperkalaemia ... hyperventilate, sodium
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