7 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... recessive salt-losing ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... #nephrology #diagnosis
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... Bartter syndrome, Gitelman ... #causes #potassium ... #low #nephrology
Causes of Apparent Life Threatening Event (ALTE) - Differential Diagnosis Algorithm
Cardiac:
 • Congenital Heart Disease
 •
Causes of Apparent ... Life Threatening Event ... Myocarditis Metabolic ... Disturbances Neurologic ... #Causes #Peds #
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... wasting from other causes ... suggests extra-renal causes ... Bartter syndrome, Gitelman ... #diagnosis #Algorithm
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
salt-losing tubulopathies ... hypomagnesemia • Metabolic ... Hypochloremic metabolic ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... Hypovolemia, UNa ... deficiency, Salt-losing ... tubal acidosis and metabolic ... #Causes #nephrology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... - Bartter - Gitelman ... Differential #Diagnosis #Algorithm ... #Pathophysiology ... #Nephrology #Chloride