12 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... Hypomagnesemia; hypokalemia ... disturbances (including hypokalemia ... Potassium #Binding #Hyperkalemia
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... #Management #Hyperkalemia ... #pharmacology #table ... #comparison #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... Bartter syndrome, Gitelman ... @priti899 #Hypokalemia ... #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... alkalosis • Normal or low ... pressure Labs: • Hypokalemia ... pathophysiology #Hypokalemia
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... recessive salt-losing ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... Pathophysiology #nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Diagnosis Algorithm ... Bartter's syndrome, Gitelman's ... syndrome #Hypokalemia ... #nephrology #causes
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Algorithm for patients ... with hypokalemia ... Bartter syndrome, Gitelman ... syndrome #hypokalemia ... #diagnosis #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... evaluating hypokalemia ... in evaluating hypokalemia ... Bartter syndrome, Gitelman ... @krithicism #Hypokalemia
Algorithm for Management of Acute and Chronic Hyperkalemia
Acute Hyperkalemia:
 - IV calcium (10 mL of 10%)
Algorithm for Management ... Acute and Chronic Hyperkalemia ... Acute Hyperkalemia ... Chronic Hyperkalemia ... optimization) #Hyperkalemia
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... Inexpensive - Treats hypocalcemia ... Lowers level of low-density ... increased risk of low ... #Table #Comparison