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Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... , CLL Acute leukemias ... Chronic leukemia ... develop leukostasis syndrome ... • Tumor lysis syndrome
Hyperviscosity Syndrome - Causes and Treatment - Waldenstrom macroglobulinemia (most common) / Plasmapheresis - Multiple
Hyperviscosity Syndrome ... Plasmapheresis - Leukemia ... Hydroxyurea - Leukemia ... Hyperviscosity #Syndrome
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... • Most common leukemia ... - Leukemia cutis ... • Richter’s Syndrome ... • Sezary syndrome
Isolated Indirect Bilirubinemia in Leukemia • Etiologies for Isolated Indirect Bili • Gilbert's Syndrome • What
Bilirubinemia in Leukemia ... • Gilbert's Syndrome ... Bilirubinemia #Leukemia
Priapism Secondary Causes: Medications- intracavernosal injections, anticoagulants, PDE5 inhibitors, alpha blockers, methylphenidate, cocaine Any hyperviscosity syndrome (SCD, leukemia,
hyperviscosity syndrome ... (SCD, leukemia,
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Acute Eosinophilic Leukemia ... Hypereosinophilic Syndrome ... Chronic Eosinophilic Leukemia
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Arthritis, Sjogren Syndrome ... Disease, Behcet Syndrome ... Primary: Lymphoma, Leukemia ... Postcardiac Injury Syndrome
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Wiskott-Aldrich syndrome ... Cancer: • Leukemia
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... dermatosis (Sweets Syndrome ... certain types of leukemia ... Panniculitis - Leukemia ... - Lupus - Leukemia
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Leukemia, Tumour ... Non-lmmune: • HELLP Syndrome
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