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diagnosis management cdc treatment differential pathophysiology algorithm ckd pharmacology infectiousdiseases nephrology lifecycle parasite infections causes clinical guidelines hivaids opportunistic hiv
Leukocoria on Ocular Examination #Leukocoria #Ocular #PhysicalExam #clinical #video #ophthalmology #retinoblastoma #pediatrics
Leukocoria on Ocular ... Examination #Leukocoria ... ophthalmology #retinoblastoma
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 Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma: ... Unilateral Somatic Retinoblastoma ... Bilateral Germline Retinoblastoma ... Complications: • Leukocoria ... Strabismus #Retinoblastoma
Assessing and referring childhood cancers #Diagnosis #PrimaryCare #Peds #ChildhoodCancers #ClinicalFeatures #Lymphoma #Wilms #Leukemia #Retinoblastoma #BMJ
Wilms #Leukemia #Retinoblastoma
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia Clinical - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
- Positive: CD2 ... , CD3, CD8 - Loss ... of CD5 and/or CD7 ... Rarely can be CD4
Retinoblastoma - MRI • Most common intra-ocular neoplasm in children. • Clinical Presentation: leukocoria (loss of
Retinoblastoma - ... Presentation: leukocoria ... developing trilateral retinoblastoma ... DrAmarChotai #Retinoblastoma
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- T-cell - CD7 ... , CD3 Chronic ... - B-cell CD5
Presentation of malignant disease in children Pre-school (<5 years old) - Acute lymphoblastic leukaemia
Wilm tumour - Retinoblastoma
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
- Hx of AKI/CKD ... US w/ PVR - CPK ... 21% - AKI on CKD
The Cell Cycle The cell cycle is the series of tightly regulated steps that controls cell growth
Cyclin-dependent kinases (CDKs ... factor (regulators) Retinoblastoma ... Cyclin-dependent kinase #CDK ... transcription factor #Rb #Retinoblastoma
Eosinophils (Eos) and hypereosinophilia (HE) Caused by eosinophilopoietic cytokines Common causes: - Drug reaction - Helminth infection -
CD3-CD4+ T cells
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