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The fourth pattern includes abnormalities that result in decreased lung attenuation or air-filled lesions.
These include:
- Emphysema
-
on the basis of HRCT ... #Pulmonary #CTChest ... LowAttenuation #Differential ... #Diagram #Comparison ... #SignetRing #RadiologyAssistant
Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases
Upper lung zone ... (centrilobular emphysema ... bronchiolitis (RB-ILD ... is seen in: - UIP ... #Pulmonary #HRCT
UIP with honeycombing (left) and chronic HP (right)
Differential diagnosis of Hypersensitivity Pneumonitis.
Subacute stage:
- RB-ILD: seen in
chronic HP (right) Differential ... centrilobular emphysema ... show very similar HRCT ... #CTChest #UIP # ... Comparison #Chronic
The idiopathic interstitial pneumonias (IIPs) comprise a heterogenous group of disorders. 
They represent fundamental responses of
indicates unknown cause ... morphologic findings on HRCT ... #Pulmonary #CTChest ... IdiopathicInterstitialPneumonia #ILD ... #Findings #RadiologyAssistant
Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
Differential diagnosis ... in interstitial lung ... UIP can be suspected ... #Pulmonary #CXR ... #RadiologyAssistant
On the left a typical case of panlobular emphysema.
There is uniform destruction of the underlying architecture
left a typical case ... the other hand, mild ... difficult to detect on HRCT ... #CTChest #Panlobular ... #RadiologyAssistant
Cavities frequently arise within a mass or an area of consolidation as a result of necrosis.
We
can heal and end up ... the surrounding lung ... without associated pulmonary ... #CTChest #Cavity ... #Comparison #RadiologyAssistant
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Lung Toxicity Summary ... Direct cytotoxic lung ... Exclusion of other ILDs ... confirmatory findings on HRCT ... #diagnosis #management
On the left a smoker with RB-ILD with subtle HRCT-findings.
The dominant pattern is ground glass opacification.
Additional
are paraseptal emphysema ... there is a broad differential ... #Clinical #Radiology ... #CTChest #RBILD ... #RadiologyAssistant