11 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... disease (MCTD), Drug-induced ... (SLE), Sjogren's ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... : The ANA patterns ... Patterns and Associated ... #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Auto-Antibodies: - ANA ... Mimickers: Drug-induced ... #Diagnosis #autoantibodies ... #rheumatology
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Lupus Erythematosus ... Lupusreference #DrugInduced ... #pharmacology # ... risk #differential ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Anti-Ro/SSA autoantibodies ... alopecia Differential ... Arthritis: • Joint pain ... extremities Drug ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... of autoantibodies ... Systemic Lupus Erythematosus ... Lupusreference #druginduced ... #table #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... • Is there a pattern ... morning • Effusion leukocyte ... #Differential # ... Diagnosis #MSK #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
fingers, or pain ... the face (many differential ... has been ruled out ... clues #system #erythematosus ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... ) pattern: antibodies ... ) pattern: is usually ... SLE) • Urinalysis ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... atherosclerotic disease, drug ... ischemia • Skin: Erythematous ... viral infection, drug ... #Diagnosis #Rheumatology