11 results
diagnosis hematology management mds myelodysplastic aids algorithm anemia aplastic associated cancer chronic cll comparison cppd dementia differentiation disorder hand hiv
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... develop leukostasis syndrome ... smear: Blasts APML ... • Tumor lysis syndrome ... #Hematology #Oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... #APML #diagnosis ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute leukemia ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... lymphoma & Acute leukemia ... (both ALL and AML ... malignancies Treatments ... #TLS #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
anemia DDX: Rule Out ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... #diagnosis #hematology ... #oncology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... disease states Pathophysiology ... • Metabolic syndrome ... Intracellular (leukocyte ... #Comparison #rheumatology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
sex • Metabolic syndrome ... Intracellular (leukocyte ... cortical bone Treatment ... treatment; consider ... #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... virus (EBV) • Leukemia ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... Findings: • Rule out ... The clinical syndrome ... Treatment: • HAART ... treatment • Cognitive
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