11 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... cases • Sjögren syndrome ... Vasculitis: • ... Microscopic polyangiitis ... antibodies #diagnosis #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
their Disease Associations ... - Vasculitis, e.g ... - Vasculitis, e.g ... Microscopic polyangiitis ... diagnosis #table #rheumatology
ANCA-Associated Vasculitis
There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... inflammation: • Microscopic ... #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... • ANCA Associated ... : - Microscopic ... Disease • Cogan syndrome ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... ): • Microscopic ... mucositis - Rash ... Dx: GPA, EGPA, microscopic ... #rheumatology #
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential ... Diagnosis Algorithm ... Sjogren's, GPA, EGPA, Microscopic ... Measurement of antinuclear ... #Differential #
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Using fluorescence microscopy ... SLE), Sjogren's Syndrome ... #patterns #rheumatology ... #diagnosis #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... , mucositis • Rash ... )): Microscopic ... Diagnosis #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... reticularis Differential ... Polyarteritis nodosa • Microscopic ... • Goodpasture syndrome ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... vasculitis, rheumatoid ... Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... Erythematosus #Diagnosis #Rheumatology