17 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Hepatopathy • Acute ... injury) • Ischemic ... ) • Non-hepatic ... #Diagnosis #hepatology ... #transaminitis
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Injury ... more specific for hepatic ... #Cholestatic #Transaminitis ... #diagnosis #differential ... #hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
fibrosis - Acute ... fatty liver of ... #Causes #diagnosis ... #differential # ... hepatology #SAAG
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... #Injury #Differential ... #Diagnosis #Causes ... #hepatology
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
- Differential ... Diagnosis Algorithm ... Infiltrative disease • Acute ... liver failure ... #Hepatology #causes
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 20x normal - Acute ... #Injury #hepatology ... #LFTs #transaminitis ... #differential # ... diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... disease, Hepatic ... dechallenge • Acute ... disorder (e.g. ascites ... #Injury #Diagnosis
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... of portal HTN: ascites ... • Cirrhosis/acute ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... • Hepatic vein: ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
injury < 26 weeks ... replaced by non-hepatic ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis