13 results
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Product Types: • Leukocyte ... proteins on plts, leukocytes ... Causes purpura & ... #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
proteins on plts, leukocytes ... Causes purpura & ... TRALI): Leading cause ... #diagnosis #management ... #hematology #reactions
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
TRALI vs TACO - Transfusion ... Reactions TRALI ... without other cause ... #Reactions #hematology ... #diagnosis #comparison
Differential Diagnosis - Noninfectious Causes of Fever

CRITICAL DIAGNOSES:
 - Acute myocardial infarction
 - Pulmonary embolism or
Noninfectious Causes ... insufficiency - Transfusion ... reaction - Pulmonary ... Malignancy - Gout ... Noninfectious #Causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... reaction, Paroxysmal ... Extravascular #Causes ... #hematology #anemia
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... prosthetic valve • Transfusion ... reactions ex. ... #Differential #Diagnosis ... #hematology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... Allergen-specific lgE causes ... Examples: Acute transfusion ... recruitment of leucocytes ... classification #comparison
Causes of Pseudocellulitis - Differential Diagnosis Framework for Cellulitis Mimics

Cellulitis: Deep skin and subcutaneous fat infection

Pseudo
- Differential Diagnosis ... avoid allergic reactions ... Pseudocellulitis: • Drug reaction ... Sweet syndrome • Gout ... #dermatology #skin
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
culture used to diagnose ... A reaction to phagocytosed ... Intracellular (leukocyte ... #Comparison #rheumatology ... #Diagnosis
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Gout - Diagnosis ... A reaction to phagocytosed ... Intracellular (leukocyte ... severe allergic reactions ... #treatment #rheumatology